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Glutathione is a powerful antioxidant present in every cell of the body. The two forms of glutathione are reduced glutathione (GSH or L-glutathione) and oxidized (GSSG). GSH is the active form that helps combat oxidative stress.
GSH protects cellular mitochondria by clearing environmental toxins and binding to heavy metals as a natural chelator. It also plays an important role in detoxification, building a strong and healthy immune system, enzyme function, and other health benefits.
Some of the major functions of glutathione include:
You can read more about how glutathione benefits the body in this Ingredient Spotlight post.
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Glutathione is a tripeptide (a group of three amino acids joined by peptide bonds) and includes the amino acids glutamine, glycine, and cysteine. Glutathione also contains sulfur chemical groups, which help bond free radicals and heavy metals and remove them.
Under ideal circumstances, the body would recycle the components needed for glutathione synthesis. Unfortunately, there may be insufficient levels of glutathione available because of:
In these cases, supplements can support the glutathione recycling process and ensure the body has adequate glutathione levels available.
In autoimmune diseases, an overactive immune response can damage the body's tissues and deplete its resources, limiting its ability to fight off pathogens and infections.
Examples of autoimmune diseases include
Chronic inflammation exists in most autoimmune disorders, which can damage the body in various ways. One issue with chronic inflammation is that it produces unstable, reactive oxygen species (ROS). ROS are free radicals, that the body can absorb from food, water, medicine, and air.
Free radicals are unstable because they have unpaired electrons. As free radicals look for electrons to pair with, they can damage mitochondria, DNA, RNA, and proteins, which leads to oxidative stress.
Endogenous GSH is a free radical scavenger and helps regulate the body's immune response. As an antioxidant, glutathione bonds with free radicals, thereby stabilizing them and preventing further damage.
Chronic inflammation can deplete glutathione levels, impacting overall immune function. Glutathione deficiency can lead to numerous health problems and worsen oxidative damage, perpetuating the cycle of chronic inflammation.
The myelin sheath is the lipid-rich coating around the axons of nerve cells. Myelin provides a protective cover and increases the electrical impulse rate along the axon. The insulating role of the myelin sheath is essential for
Demyelination is the loss or deterioration of the myelin sheath and occurs in neurogenerative autoimmune diseases like Guillain-Barre and multiple sclerosis (MS).
Previous research has shown that patients with MS have an altered GSH homeostasis. New research is exploring ways to combat oxidative stress and prevent neurodegenerative processes associated with MS by raising glutathione concentrations.
Other natural ways to support remyelination* include:
MS and other autoimmune disorders are very serious health conditions with many side effects, so be sure to get approval from your personal healthcare team before making any changes to your diet, lifestyle, and supplementation practices.
There's no doubt that glutathione is an incredible antioxidant with multiple health benefits. If you're suffering from autoimmune disease, chronic stress, chronic inflammation, or for some reason have low glutathione, the additional boost provided by a supplement could help improve your symptoms and quality of life.*
Remember the benefits of liposomal supplements, like Amandean's Liposomal Glutathione and Liposomal Vitamin C, are significant. Liposomal encapsulation produces supplements that have greater bioavailability, better absorption, and won't irritate the gut.
-Stephanie Hodges, MS in Nutrition and Exercise Science
Glutathione is a powerful antioxidant present in every cell of the body.
Endogenous GSH is a free radical scavenger and helps regulate the body's immune response.
Chronic inflammation can deplete glutathione levels, impacting overall immune function.
The myelin sheath is the lipid-rich coating around the axons of nerve cells.
Omega-3s are essential fats, so must be consumed through foods or supplements.
If you're suffering from autoimmune disease, chronic stress, chronic inflammation, or have low glutathione levels, the additional boost provided by a daily supplement could help improve your symptoms and quality of life.
